Fig. 2

An example workflow for creation, execution, and post-processing API requests to retrieve protein information from UniProt: The ‘String Manipulation’ node accepts a column with UniProt IDs listed and an API request is created (as string). The ‘GET Request’ node executes the requests generated in the previous step. The ‘XPath’ node extracts PDB IDs associated with a certain UniProt ID (if available). For a detailed description of how to retrieve UniProt IDs we refer the reader to the subsequent section