Fig.7

Histograms of WDR5 compounds distribution after 2nd layer filtering for hit calling. Molecules that passed the chemical physical-property filters are further calculated for A SAScore, B QED score and C GBVI/WSA ΔG score with the cutoffs in Table 1. In each histogram, blue means compounds that passed both the other two hit calling filters, and red means the compounds that failed either of the other two filters