Fig. 4
From: Reaction rebalancing: a novel approach to curating reaction databases
Simplified overview of the functional process in SynRBL. The rule-based method is applied if the reaction is carbon-balanced but otherwise unbalanced in either the reactant or the product side. The MCS-based method is used if both sides are unbalanced, the rule-based method fails, or the reaction has a carbon imbalance in the first place. The output is either the balanced reaction if the method is successful or the unmodified input in case SynRBL can not find a solution. The Rule-based and MCS-based method blocks abstract the respective procedures for the sake of readability. Supplementary Fig. S1 and Fig. S2 contain a more detailed in-depth view on these blocks with example data