Fig. 2

Example curve fits illustrating different outcomes: (a) and (b) show dose-response curves where no activity was evident (hitcall_c = 0); the upper panel has three outlier points. (c) and (d) illustrate intermediate confidence of activity based on the hill model. (e) and (f) show strong confidence in activity; the upper panel required a ‘forced hill’ fit, and the lower panel fit with the ‘hill’ model. The ‘constant’ model and cutoff are shown in all panels. AEID = assay endpoint ID and SPID = species ID